China-based mostly Hutchmed introduced receipt of a complete response letter from the FDA, stating that the agency can now now not approve the tyrosine kinase inhibitor surufatinib for developed neuroendocrine tumors without red meat up from a multiregional scientific trial.
Coherus and Junshi Biosciences also purchased a total response letter for PD-1 inhibitor toripalimab as a medications for developed or metastatic nasopharyngeal carcinoma over disorders connected to a “quality route of swap.”
AstraZeneca and Daiichi Sankyo introduced that the FDA remodeled an accelerated approval to burly approval of trastuzumab deruxtecan (Enhertu) for unresectable or metastatic HER2-optimistic breast most cancers previously treated with anti-HER2 remedy.
The tobacco industry has agreed in conception to a settlement that lays out phrases for corrective promoting connected to the doable health dangers of tobacco employ, as required by the 2006 federal court docket dedication in United States v Philip Morris. (American Cancer Society)
A section I/II trial of sitravatinib and nivolumab (Opdivo) for previously treated renal cell carcinoma produced a disease reduction watch over price of 88.1% and survival price of 80% after a median be aware-up of 18.7 months. (University of Texas MD Anderson Cancer Center, Science Translational Medication)
Novartis introduced it has voluntarily suspended manufacturing at two radioligand manufacturing facilities and has hasty halted screening and enrollment in scientific trials involving the radioligand products, pending an investigation into doable quality disorders in the manufacturing route of.
A randomized, section III trial confirmed that topical imiquimod is a receive and effective alternative to surgical scheme for vulvar excessive-grade squamous intraepithelial lesions. (The Lancet)
A uncommon but aggressive make of uterine most cancers looks to be using most contemporary will increase in uterine most cancers mortality, besides the colossal mortality disparity affecting Black females. (JAMA Oncology)
A blood test that most primary care physicians would possibly perchance perchance per chance make all over routine care confirmed promise for early detection of ovarian most cancers. (University of Manchester)
A brand unusual most cancers immunotherapy approach that entails coaching T cells to detect mutations specific to most cancers cells confirmed promise in preclinical testing. (Memorial Sloan Kettering Cancer Center, Nature Medication)
An Idaho physician who attributed — without offering proof — a surge in most cancers conditions to COVID vaccine-triggered immune harm has been accused of most cancers misdiagnosis in a criticism to a medical overview board. (Idaho Capital Solar)
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Charles Bankhead is senior editor for oncology and in addition covers urology, dermatology, and ophthalmology. He joined MedPage This day in 2007. Apply
