BIOTECH AND PHARMANEWS

José Eduardo Sousa, ‘Father’ of Drug-Eluting Stents, Dies at 88

Interventional cardiologist José Eduardo Sousa, MD, PhD, who helped revolutionize the treatment of coronary artery disease with drug-eluting stents, died Sunday in Brazil at the age of 88.

In 1966, Sousa completed the important coronary angiography in Brazil and in 1986 grew to become the important to implant the Palmaz-Schatz stent in a human being, in step with the Brazilian Society of Hemodynamics and Interventional Cardiology, which launched the loss of its first president on Twitter.

In 1999, Sousa and colleagues conducted the important-in-man trial of a drug-eluting stent covered with sirolimus, reporting no re-stenosis, an Achilles heel of stenting in the intervening time, at 8-month apply-up in 30 consecutive patients.

Patrick Serruys, MD, PhD, co-author of these seminal results, suggested theheart.org | Medscape Cardiology, “It’s a extraordinarily sad day because he became an very good searching particular person and we interacted at a important moment in cardiology.”

Serruys recalled these demanding early days with Sousa treating 15 patients in 2 days and returning about a months later to assassinate apply-up coronary angiography and what became then a recent scheme, intravascular ultrasound, in a single day. They popular with champagne and by 8 PM he became on his manner attend to his dwelling in the Netherlands.

Dr José Eduardo Sousa helped revolutionize the treatment of coronary artery disease with drug-eluting stents and is taken into epic a pioneer in the self-discipline of interventional cardiology.

“We opened a brand recent generation,” said Serruys, now with Nationwide College of Eire, Galway. “The important-in-man is one thing very refined since you would even bask in this type of simply responsibility and we had to expose the stent is eluting a drug that’s if truth be told outmoded in cancer. The patient has to listen to to you and have confidence in you as a health care provider.”

That job became made more straightforward because Sousa had monumental empathy for the patient and understood what they had been enduring, Serruys said. “He became a light, bespectacled man — that’s how I’ll continuously have in mind Eduardo.”

On Twitter, cardiologists answered to the details, heralding Sousa because the “father of drug-eluting stents” and a “big” in the self-discipline of interventional cardiology.


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Roxana Mehran, MD, Icahn College of Treatment at Mount Sinai in Unique York City, tweeted: “He led the sphere in revolutionary technologies, the first to assassinate procedures we now select as a correct with power, humility, and fancy for his [patients].”


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Gregg Stone, MD, furthermore with Mount Sinai, said Sousa became “certainly one of a form, a pioneer, and role model who intended so powerful to medication.”


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Sousa became born January 30, 1934 in Pedreiras, Brazil and executed his scientific level at the Federal College of Pernambuco in Brazil in 1958, in step with the Brazilian Academy of Treatment. He went on to whole a pediatric cardiology specialization at Harvard College in 1963, a fellowship in coronary arteriography at the Cleveland Health center, and a doctorate in cardiology from the College of São Paulo in 1969.

Sousa became the technical director of the Dante Pazzanese Cardiology Institute in São Paulo between 1983 and 2004, and directed its Interventional Heart in Structural Coronary heart Diseases. He furthermore served as a professor and advisor at the College of São Paulo since 1993.

He published bigger than 550 articles, participated in bigger than 120 analysis initiatives, and has over 210 published guide chapters.

Sousa is survived by his spouse, Amanda, and a daughter, Andrea.

Put together Patrice Wendling on Twitter: @pwendl For more from theheart.org | Medscape Cardiology, apply us on Twitter and Fb .

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